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Alexandra M. Binder, Camila Corvalan, Verónica Mericq, Ana Pereira, José Luis Santos, Steve Horvath, John Shepherd, and Karin B. Michels. Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls. Epigenetics [Accepted – In process]

Alexandra M. Binder, Camila Corvalan, Ana Pereira, Antonia M. Calafat, Xiaoyun Ye, John Shepherd, and Karin B. Michels. Pre-pubertal and Pubertal Endocrine Disrupting Chemicals Exposure and Breast Density among Chilean Adolescents. Cancer Epidemiology, Biomarkers, and Prevention [Accepted – In process]

Ludovic Barault, Alessio Amatu, Giulia Siravegna, Agostino Ponzetti, Sebastian Moran, Andrea Cassingena, Benedetta Mussolin, Chiara Falcomatà, Alexandra M Binder, Carmen Cristiano, Daniele Oddo, Simonetta Guarrera, Carlotta Cancelliere, Sara Bustreo, Katia Bencardino, Sean Maden, Alice Vanzati, Patrizia Zavattari, Giuseppe Matullo, Mauro Truini, William M Grady, Patrizia Racca, Karin B Michels, Salvatore Siena, Manel Esteller, Alberto Bardelli, Andrea Sartore-Bianchi, and Federica Di Nicolantonio. Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer. Gut 2017 Oct 5. pii: gutjnl-2016-313372. [Epub ahead of print]. PMID: 28982739 

Sanne D. van Otterdijk, Alexandra M. Binder, and Karin B. Michels. Locus-specific DNA methylation in the placenta is associated with levels of pro-inflammatory proteins in cord blood and they are both independently affected by maternal smoking during pregnancy. Epigenetics 2017 Aug 18:0. [Epub ahead of print]. PMID: 28820654 

Aggeliki Tserga, Alexandra M. Binder, and Karin B. Michels. Impact of folic acid intake during pregnancy on genomic imprinting of IGF2/H19 and 1-carbon metabolism. FASEB 2017 Aug 4. pii: fj.201601214RR. [Epub ahead of print]. PMID: 28778973

Sanne D. van Otterdijk, Alexandra M. Binder, Katarzyna Szarc vel Szic, Julia Schwald, and Karin B. Michels. DNA methylation of candidate genes in peripheral blood from patients with type 2 diabetes or the metabolic syndrome. PloS One 2017; 12: e018095. PMCID: PMC5519053

Alexandra M. Binder*, Juan J. Carmona*, William P. Accomando Jr.*,  John N. Hutchinson, Lorena Pantano, Benedetta Izzi, Allan C. Just, Xihong Lin, Joel Schwartz, Pantel S. Vokonas, Sami S. Amr, Andrea A. Baccarelli and Karin B. Michels. Empirical comparison of reduced representation bisulfite sequencing and Infinium BeadChip reproducibility and coverage of DNA methylation in humans. npj Genomic Medicine 2017; 2:13. PMC Journal – In Process; link

Jessica LaRocca, Alexandra M. Binder, Thomas F. McElrath, and Karin B. Michels. First-Trimester Urine Concentrations of Phthalate Metabolites and Phenols and Placenta miRNA Expression in a Cohort of U.S. Women. Environ Health Perspect. 2016; 124:380-387. PMID: 26090578

Alexandra M. Binder, Jessica LaRocca, Corina Lesseur, Carmen J. Marsit, and Karin B. Michels. Epigenome-wide and transcriptome-wide analyses reveal gestational diabetes is associated with alterations in the human leukocyte antigen complex. Clinical Epigenetics. 2015 Aug 5. PMID: 26244062

Timothy M. Barrow*, Ludovic Barault*, Rachel E. Ellsworth, Holly R. Harris, Alexandra M. Binder, Allyson L. Valente, Craig D. Shriver and Karin B. Michel. Aberrant methylation of imprinted genes is associated with negative hormone receptor status in invasive breast cancer. International Journal of Cancer. 2015 Jan 5. PMID: 25560175

Alexandra M. Binder*, Jessica LaRocca*, Thomas F. McElrath and Karin B. Michels. The Impact of First Trimester Phthalate and Phenol Exposure on IGF2/H19 Genomic Imprinting and Birth Outcomes. Environmental Research. 2014 Aug. PMID: 24972507

Amy L. Non, Alexandra M. Binder, Laura D. Kubzansky, and Karin B. Michels. Genome-wide DNA methylation in neonates exposed to maternal depression, anxiety, or SSRI medication during pregnancy. Epigenetics.2014 July 9(7). PMID: 24751725

Benedetta Izzi, Alexandra M. Binder, and Karin B. Michels. Pyrosequencing evaluation of widely available bisulfite conversion methods: considerations for application. Medical Epigenetics 2014 2: 28-36. PMCID: PMC4058339 

 Alexandra M. Binder and Karin B. Michels. The causal effect of red blood cell folate on genome-wide methylation in cord blood: A Mendelian Randomization approach. BMC Bioinformatics. 2013 Dec 4;14:353. PMCID: PMC3879006

Karin B. Michels, Alexandra M. Binder, Sarah Dedeurwaerder, Charles B. Epstein, John M. Greally, Ivo Gut, E. Andres Houseman, Benedetta Izzi, Karl T. Kelsey, Alexander Meissner, Aleksandar Milosavljevic, Kimberly D. Siegmund, Christoph Bock*, and Rafael A. Irizarry.* Recommendations for the design and analysis of epigenome-wide association studies. Nature Methods. 2013 Oct;10(10):949-55. PMID: 24076989

Amy L. Non, Alexandra M. Binder, Ludovic Barault, Rebecca C. Rancourt, Laura D. Kubzansky, and Karin B. Michels. DNA methylation of stress-related genes and LINE-1 repetitive elements across the healthy human placenta. Placenta. 2012 Mar 33(3): 183–187. PMCID: PMC3308680